CASE REPORTS ON PARVOVIRUS B19

INFECTION IN REGINA

	Case 1	Case 2	Case 3	Case 4	Case 5	Case 6
GA at diagnosis (wks)	12	17	27	24	32	30
Fetal Hydrops: - Pleural effusion - Pericardial effusion - Ascites - Anasarca	No No No No	Yes(*) No Yes(*) No	Yes Yes Yes No	Yes No Yes No	Yes Yes Yes Yes	Yes Yes Yes No
Myocarditis	No	No	Yes	No	Yes	No
Pericarditis	No	No	No	No	Yes	No
Liver involvement	No	No	No	No	Yes	No
Placentomegaly (cm)	Yes (5)	Yes (7)	Yes (9)	Yes (8)	Yes (9)	Yes (7)
Structural anomalies	No	No	No	No	No	No
Umbilical artery RI	Not done	Normal	ABS EDF	Normal	Rev EDF	Normal
Ductus venosus waveform	Not done	Normal	Abnormal (**)	Normal	Abnormal (**)	Normal
Progress	-	ABS EDF 19 wks Ý Fluid	Delivery 28 wks	Fluid resolve 27 wks	Delivery stat	Delivery 34 wks ß Fluid
Outcome	Demise (13 wks)	Demise (20wks)	Demise Day 3 PN	Survive	Demise Day 2 PN	Survive

(*) - Small amount of ascites and pleural effusion.
(**) - Abnormal waveform in ductus venosus is a result of reversal of the A wave (during atrial contraction).
ABS EDF = Absent end diastolic flow.
Rev EDF = Reversed end diastolic flow.